Description

(4-Butoxy-2-Fluorophenyl)Boronic Acid is a high-purity organoboron compound, specifically a boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and the development of functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic components.
• Material Science: Employed in the creation of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport materials, where its structure can influence optoelectronic properties.
• Ligand & Catalyst Development: Serves as a building block for synthesizing sophisticated ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and constructing molecular libraries.
• Fluorine Chemistry: The presence of the fluorine atom makes it a sought-after intermediate for introducing fluorine into target molecules to modulate their bioavailability, metabolic stability, and lipophilicity.

Basic Information

Product Name	(4-Butoxy-2-Fluorophenyl)Boronic Acid
CAS No.	1107603-52-0
Molecular Formula	C₁₀H₁₄BFO₃
Molecular Weight	212.03 g/mol
Synonyms	2-Fluoro-4-butoxyphenylboronic Acid; 4-Butoxy-2-fluorobenzeneboronic Acid; (2-Fluoro-4-butoxyphenyl)boronic Acid; B-(2-Fluoro-4-butoxyphenyl)boronic Acid; 2-Fluoro-4-n-butoxyphenylboronic Acid; 4-n-Butoxy-2-fluorophenylboronic Acid; 4-Butoxy-2-fluorophenylboronic Acid; (4-Butoxy-2-fluorophenyl)boronic Acid
EINECS	Contact for details

Quality Control

Our (4-Butoxy-2-Fluorophenyl)Boronic Acid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR (¹H, ¹³C, ¹¹B, ¹⁹F), and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.