Description

4'-(Trifluoromethyl)Biphenyl-3-Ylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling the efficient construction of complex molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those targeting CNS disorders and inflammation.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	4'-(Trifluoromethyl)Biphenyl-3-Ylboronic Acid
CAS No.	1107603-45-1
Molecular Formula	C13H10BF3O2
Molecular Weight	266.03 g/mol
Synonyms	[3-(4-Trifluoromethylphenyl)phenyl]boronic acid; 3-(4-Trifluoromethylphenyl)benzeneboronic acid; 3-Borono-4'-(trifluoromethyl)biphenyl; 4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-boronic acid; (3'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)boronic acid; 4'-Trifluoromethylbiphenyl-3-boronic Acid; 3-(4-Trifluoromethylphenyl)phenylboronic Acid
EINECS	Contact for details

Quality Control

Our 4'-(Trifluoromethyl)Biphenyl-3-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.