Description

3'-Trifluoromethyl-Biphenyl-4-Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing biaryl scaffolds present in numerous drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific trifluoromethyl-biphenyl motifs.
• Material Science: Serves as a precursor for organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.
• Liquid Crystal & Polymer Chemistry: Used as a monomer or intermediate in the synthesis of specialty polymers and liquid crystal materials.

Basic Information

Product Name	3'-Trifluoromethyl-Biphenyl-4-Boronic Acid
CAS No.	1106837-36-8
Molecular Formula	C13H10BF3O2
Molecular Weight	266.03 g/mol
Synonyms	[4-(3-Trifluoromethylphenyl)phenyl]boronic acid; 4-(3-(Trifluoromethyl)phenyl)benzeneboronic acid; 3'-Trifluoromethyl[1,1'-biphenyl]-4-boronic acid; 3-(Trifluoromethyl)biphenyl-4-boronic acid; 4-Borono-3'-trifluoromethylbiphenyl; B-[4-(3-Trifluoromethylphenyl)phenyl]boronic acid; 3'-Trifluoromethyl-4-biphenylboronic Acid
EINECS	Contact for details

Quality Control

Our 3'-Trifluoromethyl-Biphenyl-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.