Description

2-Bromo-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- Phenylalanine is a specialized, protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring the controlled introduction of brominated phenylalanine residues into peptide chains, enabling the study of structure-activity relationships and the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic laboratories focused on peptide-based drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled incorporation of brominated aromatic amino acids into peptide sequences.
• Peptide Drug Discovery: Used in the research and development of novel therapeutic peptides, where the bromine atom serves as a handle for further chemical modifications or as a structural probe.
• Chemical Biology Probes: Enables the synthesis of labeled or modified peptides for studying protein-protein interactions and enzyme mechanisms.
• Combinatorial Chemistry Libraries: Serves as a valuable monomer for creating diverse peptide libraries to screen for new biological activity.
• Academic & Industrial Research: Fundamental research tool for investigating peptide conformation, stability, and function.

Basic Information

Product Name	2-Bromo-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- Phenylalanine
CAS No.	1105045-64-4
Molecular Formula	C24H20BrNO4
Molecular Weight	466.33 g/mol
Synonyms	Fmoc-2-Bromo-L-phenylalanine; Fmoc-2-Br-Phe-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-bromo-L-phenylalanine; 2-Bromo-N-Fmoc-L-phenylalanine; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(2-bromophenyl)propanoic acid; Fmoc-Phe(2-Br)-OH; Boc-2-Bromo-L-phenylalanine (common related compound)
EINECS	Contact for details

Quality Control

Our 2-Bromo-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- Phenylalanine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.