Description

Methyl 6-Fluorobenzofuran-3-Carboxylate is a high-purity fluorinated benzofuran derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate the benzofuran motif into novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the fluorobenzofuran structure can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Versatile intermediate for further functionalization, including hydrolysis to the corresponding acid, amide formation, or cross-coupling reactions.
• Academic & R&D: Utilized in university and institutional laboratories for methodological studies and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	Methyl 6-Fluorobenzofuran-3-Carboxylate
CAS No.	1103768-31-5
Molecular Formula	C10H7FO3
Molecular Weight	194.16 g/mol
Synonyms	6-Fluoro-3-benzofurancarboxylic acid methyl ester; Methyl 6-fluoro-1-benzofuran-3-carboxylate; 6-Fluorobenzofuran-3-carboxylic acid methyl ester; 3-Carbomethoxy-6-fluorobenzofuran; Methyl 6-fluoro-3-benzofurancarboxylate; 6-Fluoro-3-methoxycarbonylbenzofuran; Methyl 6-fluorobenzofurane-3-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 6-Fluorobenzofuran-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0% (Standard Grade)
Purity (GC)	≥97.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.