Description

(R)-1-(Diphenylphosphino)-3-Phenylpropan-2-Amine is a chiral, bidentate P,N-ligand of significant importance in asymmetric catalysis. Its value lies in its ability to coordinate with transition metals to form highly selective catalysts, enabling the efficient synthesis of enantiomerically pure compounds. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in their synthetic routes.

Application

• As a key ligand in asymmetric hydrogenation reactions for the production of chiral amines and amino acid derivatives.
• Utilized in asymmetric C-C bond-forming reactions, such as cross-coupling and allylic substitution.
• Critical component in the development of custom transition metal catalysts for process research and development (R&D).
• Enabling technology for the synthesis of Active Pharmaceutical Ingredients (APIs) and advanced pharmaceutical intermediates.
• Used in the preparation of chiral ligands and catalysts for academic and industrial research in stereoselective synthesis.
• Application in the synthesis of specialty agrochemicals and flavors & fragrances requiring high enantiomeric purity.

Basic Information

Product Name	(R)-1-(Diphenylphosphino)-3-Phenylpropan-2-Amine
CAS No.	1103534-03-7
Molecular Formula	C21H22NP
Molecular Weight	319.38 g/mol
Synonyms	(R)-1-(Diphenylphosphino)-3-phenyl-2-propylamine; (R)-1-(Diphenylphosphino)-3-phenylpropan-2-amine; (R)-DPPPA; (R)-2-Amino-1-(diphenylphosphino)-3-phenylpropane; (R)-1-(Diphenylphosphino)-3-phenyl-2-propanamine; (R)-3-Phenyl-1-(diphenylphosphino)propan-2-amine; (R)-N-[(Diphenylphosphino)methyl]-β-phenethylamine
EINECS	Contact for details

Quality Control

Our production of (R)-1-(Diphenylphosphino)-3-Phenylpropan-2-Amine adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and enantiomeric excess is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.