Description

(S)-2-(Diphenylphosphino)-1-Phenylethylamine is a high-purity chiral phosphine-amine hybrid ligand, essential for constructing sophisticated asymmetric catalysts. This compound matters because it enables highly enantioselective transformations, critical for producing single-isomer pharmaceuticals and fine chemicals with superior efficacy and safety profiles. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in cross-coupling, hydrogenation, and hydroformylation reactions.

Application

• Asymmetric Catalysis: As a key ligand for transition metals like rhodium, iridium, and palladium to catalyze enantioselective hydrogenation and C-C bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: For the production of chiral active pharmaceutical ingredients (APIs), particularly in the synthesis of complex molecules requiring high stereochemical purity.
• Agrochemical Research: Development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Synthesis of chiral polymers and coordination complexes with unique optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis studies.
• Process Chemistry Optimization: Scaling up asymmetric synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	(S)-2-(Diphenylphosphino)-1-Phenylethylamine (Min. 97%)
CAS No.	1103533-85-2
Molecular Formula	C20H20NP
Molecular Weight	305.35 g/mol
Synonyms	(S)-(-)-2-(Diphenylphosphino)-1-phenylethylamine; (S)-2-(Diphenylphosphino)-1-phenylethanamine; (S)-Phenylethylamine-Diphenylphosphine; (S)-P,N-Ligand; (S)-DPPEN; (S)-DPPEA; (S)-Amino Phosphine Ligand; (S)-1-Phenylethylamine-2-diphenylphosphine
EINECS	Contact for details

Quality Control

Our (S)-2-(Diphenylphosphino)-1-Phenylethylamine is manufactured under strict quality control protocols to ensure a minimum purity of 97%. Each batch is characterized by modern analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Allow the container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Enantiomeric Excess (Chiral HPLC)	Min. 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.