Description

1-Isobutyryl-2-Piperidinecarboxylic Acid is a specialized piperidine derivative and a key chiral building block in organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and advanced material sectors seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides requiring specific stereochemistry for enhanced efficacy.
• Ligand and Catalyst Precursor: Serves as a starting material for creating sophisticated chiral ligands used in asymmetric catalysis.
• Peptidomimetic Research: Incorporated into peptide analogs to modify biological activity and improve metabolic stability.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic and Industrial R&D: Utilized in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	1-Isobutyryl-2-Piperidinecarboxylic Acid
CAS No.	1103336-91-9
Molecular Formula	C10H17NO3
Molecular Weight	199.25 g/mol
Synonyms	2-(2-Methylpropanoyl)piperidine-1-carboxylic Acid; 1-Carboxy-2-isobutyrylpiperidine; 2-Isobutyrylpiperidine-1-carboxylic Acid; Piperidine-1-carboxylic Acid, 2-(2-methyl-1-oxopropyl)-; 1-(Isobutanoyl)piperidine-2-carboxylic Acid; 2-Piperidinecarboxylic Acid, 1-Isobutyryl-; (RS)-1-Isobutyrylpiperidine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-Isobutyryl-2-Piperidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.