Description

4-Ethynyltetrahydro-2H-Thiopyran is a specialized heterocyclic building block featuring both a thiopyran ring and a terminal alkyne functional group. This unique molecular architecture makes it a high-value intermediate for constructing complex sulfur-containing scaffolds in advanced chemical synthesis. It is primarily utilized by pharmaceutical R&D and agrochemical research teams for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its sulfur heterocycle for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation and proteomics research due to its reactive alkyne handle for click chemistry.
• Catalyst Ligand Precursor: Utilized in the development of novel chiral ligands for asymmetric catalysis in fine chemical manufacturing.

Basic Information

Product Name	4-Ethynyltetrahydro-2H-Thiopyran
CAS No.	1100509-34-9
Molecular Formula	C7H10S
Molecular Weight	126.22 g/mol
Synonyms	4-Ethynyltetrahydro-2H-thiopyran; 4-Ethynylthiane; Tetrahydro-4-ethynyl-2H-thiopyran; 4-Ethynylthian; 4-Ethynylperhydrothiopyran; 4-Thianylethyne; 1100509-34-9
EINECS	Contact for details

Quality Control

Every batch of 4-Ethynyltetrahydro-2H-Thiopyran is manufactured under strict quality management systems. Our products undergo rigorous quality testing including HPLC, GC, and NMR analysis to ensure compliance with industry standards and precise customer requirements. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.