Description

1-Chloro-2-Fluoro-3-(2,2,2-Trifluoroethyl)Benzene is a high-value, multi-functional fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring both halogen and trifluoroethyl substituents, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart desirable properties such as chemical resistance, thermal stability, and low surface energy.
• Chemical Research & Development: A versatile reagent in organic synthesis for introducing the 2,2,2-trifluoroethyl group into aromatic systems via further functionalization.
• Fluorinated Surfactant Precursor: Used in the development of high-performance surfactants and surface treatment agents.

Basic Information

Product Name	1-Chloro-2-Fluoro-3-(2,2,2-Trifluoroethyl)Benzene
CAS No.	1099598-23-8
Molecular Formula	C8H5ClF4
Molecular Weight	212.57 g/mol
Synonyms	3-(2,2,2-Trifluoroethyl)-1-chloro-2-fluorobenzene; 2-Chloro-1-fluoro-3-(2,2,2-trifluoroethyl)benzene; 1-Chloro-2-fluoro-3-(trifluoroethyl)benzene; 2-Fluoro-6-(2,2,2-trifluoroethyl)chlorobenzene; Benzene, 1-chloro-2-fluoro-3-(2,2,2-trifluoroethyl)-; (2-Chloro-6-fluorophenyl)(trifluoro)methane (tautomeric form); 3-(Trifluoroethyl)-2-fluoro-1-chlorobenzene
EINECS	Contact for details

Quality Control

Our 1-Chloro-2-Fluoro-3-(2,2,2-Trifluoroethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.45 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.