Description

1-Bromo-4-(2,2-Difluoropropyl)Benzene is a high-purity, specialty aromatic building block containing both bromine and fluorine substituents, offering versatile reactivity for advanced synthesis. This compound is valued for its role in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique halogenated structure enables precise molecular modifications. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex organic frameworks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the difluoropropyl group can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to form biaryl structures.
• Fluorine Chemistry Research: A valuable reagent in academic and industrial R&D for studying the effects of fluorine introduction on physical and chemical properties.
• Polymer Modification: Can be incorporated as a monomer or modifier to create specialty polymers with tailored properties like chemical resistance or altered dielectric constants.

Basic Information

Product Name	1-Bromo-4-(2,2-Difluoropropyl)Benzene
CAS No.	1099598-20-5
Molecular Formula	C9H9BrF2
Molecular Weight	235.07 g/mol
Synonyms	4-Bromo-α,α-difluoropropylbenzene; 1-Bromo-4-(2,2-difluoropropyl)benzene; p-Bromo(2,2-difluoropropyl)benzene; Benzene, 1-bromo-4-(2,2-difluoropropyl)-; (2,2-Difluoropropyl)-4-bromobenzene; 4-(2,2-Difluoropropyl)bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(2,2-Difluoropropyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical properties are provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.