Description

2-Bromo-1-Fluoro-4-(2,2,2-Trifluoroethyl)Benzene is a high-value, multi-functional fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring bromine, fluorine, and a trifluoroethyl group, makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic motifs to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and bromine substituents contribute to enhanced efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving charge transport and stability.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to form complex biaryl structures.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in organofluorine chemistry and the development of fluorinated analogs.
• Specialty Polymer Modifier: Can be incorporated into polymer backbones to impart unique properties such as chemical resistance, low surface energy, and thermal stability.

Basic Information

Product Name	2-Bromo-1-Fluoro-4-(2,2,2-Trifluoroethyl)Benzene
CAS No.	1099598-18-1
Molecular Formula	C8H5BrF4
Molecular Weight	257.03 g/mol
Synonyms	1-Bromo-2-fluoro-4-(2,2,2-trifluoroethyl)benzene; 4-(2,2,2-Trifluoroethyl)-2-bromofluorobenzene; 2-Bromo-α,α,α-trifluoro-p-fluoroethylbenzene; Benzene, 2-bromo-1-fluoro-4-(2,2,2-trifluoroethyl)-; 2-Bromo-1-fluoro-4-(trifluoroethyl)benzene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-Fluoro-4-(2,2,2-Trifluoroethyl)Benzene undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.