Description

1-Fluoro-2-(2,2,2-trifluoroethyl)-4-(trifluoromethyl)benzene is a high-value, multi-fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both a trifluoroethyl and a trifluoromethyl substituent on a fluorinated benzene ring, makes it a critical intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved biological activity and environmental persistence.
• Liquid Crystal & Electronic Materials: Acts as a precursor in the synthesis of fluorinated liquid crystals and organic semiconductors for display technologies and electronic devices.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to produce specialty fluoropolymers with unique chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis & Catalysis Research: Employed as a sophisticated substrate in cross-coupling reactions, fluorination studies, and the development of new catalytic methodologies.
• Positron Emission Tomography (PET) Tracer Development: The fluorine-18 isotope can potentially be introduced for use in creating radiolabeled tracers for medical imaging.

Basic Information

Product Name	1-Fluoro-2-(2,2,2-Trifluoroethyl)-4-(Trifluoromethyl)Benzene
CAS No.	1099597-68-8
Molecular Formula	C9H5F7
Molecular Weight	246.12 g/mol
Synonyms	2-(2,2,2-Trifluoroethyl)-1-fluoro-4-(trifluoromethyl)benzene; 1-Fluoro-2-(2,2,2-trifluoroethyl)-4-(trifluoromethyl)benzene; α,α,α-Trifluoro-2-fluoro-5-(trifluoromethyl)ethylbenzene; 2-Fluoro-α,α,α-trifluoro-5-(trifluoromethyl)ethylbenzene; Benzene, 1-fluoro-2-(2,2,2-trifluoroethyl)-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 1-Fluoro-2-(2,2,2-trifluoroethyl)-4-(trifluoromethyl)benzene is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended long-term storage at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.