Description

1-Chloro-3-(3,3,3-Trifluoropropyl)Benzene is a high-value fluorinated aromatic building block designed for advanced chemical synthesis. Its unique structure, combining a chlorophenyl group with a trifluoropropyl side chain, makes it a critical intermediate for creating compounds with tailored electronic and hydrophobic properties. This product is essential for research and development in the pharmaceutical and agrochemical sectors, where it is used to introduce fluorine motifs that enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the creation of novel fluorinated drug candidates targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoropropyl group can improve lipophilicity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated components for liquid crystal displays (LCDs), contributing to improved dielectric anisotropy and response times.
• Organic Electronics: Employed in the development of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Specialty Polymer Modifier: Incorporated into polymer chains to enhance chemical resistance, reduce surface energy, and improve material performance in coatings and high-performance plastics.
• Chemical Research & Development: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Negishi) and other transformations in medicinal and synthetic chemistry research.

Basic Information

Product Name	1-Chloro-3-(3,3,3-Trifluoropropyl)Benzene
CAS No.	1099597-34-8
Molecular Formula	C9H8ClF3
Molecular Weight	208.61 g/mol
Synonyms	3-(3-Chlorophenyl)-1,1,1-trifluoropropane; m-Chloro-(3,3,3-trifluoropropyl)benzene; 1-Chloro-3-(3,3,3-trifluoropropyl)benzene; (3-Chlorophenyl)(3,3,3-trifluoropropyl)methane; 3-Chloro-α,α,α-trifluoropropylbenzene; 1099597-34-8; m-Trifluoropropylchlorobenzene
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-(3,3,3-Trifluoropropyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.