Description

1-Bromo-4-(3,3,3-Trifluoropropyl)Benzene is a high-value fluorinated aromatic building block, essential for introducing both bromo and trifluoropropyl functional groups into complex molecular architectures. This compound is critical for advanced research and development in life sciences, where precise structural modification is required to modulate the biological activity and physicochemical properties of target molecules. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients and by material scientists developing specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoropropyl group to enhance lipophilicity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) and optical devices.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials and host materials in OLED fabrication.
• Cross-Coupling Reactions: The bromo aryl moiety makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Material Science Research: Employed in the development of novel fluorinated polymers and coatings with unique surface properties and chemical resistance.

Basic Information

Product Name	1-Bromo-4-(3,3,3-Trifluoropropyl)Benzene
CAS No.	1099597-31-5
Molecular Formula	C9H8BrF3
Molecular Weight	253.06 g/mol
Synonyms	4-Bromo-α,α,α-trifluoropropylaniline; 1-Bromo-4-(3,3,3-trifluoropropyl)benzene; 4-(3,3,3-Trifluoropropyl)bromobenzene; p-Bromo(3,3,3-trifluoropropyl)benzene; (3-(4-Bromophenyl)-1,1,1-trifluoropropane); 4-Bromo-1-(3,3,3-trifluoropropyl)benzene; Benzene, 1-bromo-4-(3,3,3-trifluoropropyl)-; 1099597-31-5
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(3,3,3-Trifluoropropyl)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.