Description

3-{[(2E)-3-(2-Fluorophenyl)Prop-2-Enoyl]Amino}Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a fluorinated cinnamoyl moiety, making it a valuable synthetic intermediate for advanced research and development. This compound is engineered to provide consistent reactivity and purity, which is critical for constructing complex molecular architectures in pharmaceutical and agrochemical discovery. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for applications in medicinal chemistry, peptide mimetics, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and protease inhibitor research.
• Medicinal Chemistry Research: Used to introduce fluorinated phenyl and acrylamide pharmacophores into target molecules to modulate bioavailability and binding affinity.
• Peptidomimetics & Conjugation: Serves as a versatile linker or side-chain component in the design of peptide analogs and bioconjugates.
• Agrochemical Development: Employed in the research and synthesis of new-generation herbicides and fungicides with enhanced activity.
• Chemical Biology Probes: Utilized to create fluorescent or affinity tags for studying protein-ligand interactions and cellular processes.
• Material Science: Potential monomer or cross-linker for specialty polymers requiring specific optical or electronic properties.

Basic Information

Product Name	3-{[(2E)-3-(2-Fluorophenyl)Prop-2-Enoyl]Amino}Propanoic Acid
CAS No.	1098380-51-8
Molecular Formula	C12H12FNO3
Molecular Weight	237.23 g/mol
Synonyms	(2E)-3-(2-Fluorophenyl)-N-(2-carboxyethyl)acrylamide; 3-[(E)-3-(2-Fluorophenyl)acrylamido]propanoic Acid; 2-Fluoro-N-β-alanyl-cinnamamide; β-Alanine, N-[(1E)-3-(2-fluorophenyl)-1-oxo-2-propen-1-yl]-; 3-[(3-(2-Fluorophenyl)acryloyl)amino]propanoic Acid; Fluorinated Cinnamoyl-β-alanine; 1098380-51-8; FCAA
EINECS	Contact for details

Quality Control

Our 3-{[(2E)-3-(2-Fluorophenyl)Prop-2-Enoyl]Amino}Propanoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.