Description

2,4-Difluoro-5-Nitrobenzamide is a high-purity, multi-functional aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and amide groups alongside fluorine substituents, makes it a valuable precursor for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific enzyme pathways.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and other functional materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex organic dyes and pigments due to its nitro-aromatic core.
• Chemical Biology Probe Development: Utilized in academic and industrial R&D to create molecular probes for studying biological processes.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to form complex biaryl structures.

Basic Information

Product Name	2,4-Difluoro-5-Nitrobenzamide
CAS No.	1097799-57-9
Molecular Formula	C7H4F2N2O3
Molecular Weight	202.12 g/mol
Synonyms	5-Nitro-2,4-difluorobenzamide; 2,4-Difluoro-5-nitrobenzamide; Benzamide, 2,4-difluoro-5-nitro-; 2,4-Difluoro-5-nitro-benzamide; 1097799-57-9 (CAS)
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-5-Nitrobenzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality ensures a reliable supply of this critical intermediate for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.