Description

tert-Butyl 2-Ethynylbenzylcarbamate is a specialized organic building block featuring both a carbamate protecting group and a terminal alkyne moiety. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and polymer synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring alkyne-azide cycloaddition (Click Chemistry) for bioconjugation.
• Medicinal Chemistry Research: Used in the discovery and development of new drug candidates, serving as a precursor for compounds with potential biological activity.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and pesticides.
• Polymer & Material Science: Monomer or cross-linking agent for creating specialty polymers, dendrimers, and functionalized surfaces.
• Chemical Biology Probes: Enables the labeling and study of biomolecules through its reactive alkyne handle.
• Ligand & Catalyst Development: Serves as a precursor for novel ligands used in catalytic systems.

Basic Information

Product Name	tert-Butyl 2-Ethynylbenzylcarbamate
CAS No.	1097731-47-9
Molecular Formula	C₁₄H₁₇NO₂
Molecular Weight	231.29 g/mol
Synonyms	tert-Butyl N-[(2-ethynylphenyl)methyl]carbamate; Carbamic acid, N-[(2-ethynylphenyl)methyl]-, 1,1-dimethylethyl ester; 2-Ethynylbenzylcarbamic acid tert-butyl ester; N-(2-Ethynylbenzyl)carbamic acid tert-butyl ester; N-Boc-2-ethynylbenzylamine; Boc-2-ethynylbenzylamine; (2-Ethynylphenyl)methyl tert-butylcarbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Ethynylbenzylcarbamate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.