Description

5-Bromo-1,3-Oxazole-4-Carbonitrile is a versatile and high-value heterocyclic building block used in advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of new generation herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a precursor for functionalized polymers and advanced organic electronic materials due to its electron-withdrawing nitrile and bromo substituents.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes to study biological systems.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse compound libraries.
• Heterocyclic Chemistry: A fundamental scaffold for the synthesis of more complex fused heterocyclic systems with potential biological activity.

Basic Information

Product Name	5-Bromo-1,3-Oxazole-4-Carbonitrile
CAS No.	1097306-76-7
Molecular Formula	C4HBrN2O
Molecular Weight	172.96 g/mol
Synonyms	5-Bromooxazole-4-carbonitrile; 4-Cyano-5-bromooxazole; 5-Bromo-4-cyanooxazole; 1,3-Oxazole-4-carbonitrile, 5-bromo-; 5-Bromo-1,3-oxazole-4-carbonitrile; 5-Bromooxazole-4-carbonitrile; 4-Oxazolecarbonitrile, 5-bromo-
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,3-Oxazole-4-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch to guarantee compliance with your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.