Description

5-Bromo-2-(Difluoromethoxy)Anisole is a high-purity, advanced pharmaceutical intermediate characterized by its unique bromine and difluoromethoxy substituents. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its halogenated structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and material science applications.
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing complex aromatic ethers and exploring new fluorination chemistry.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals used in electronics and advanced materials.

Basic Information

Product Name	5-Bromo-2-(Difluoromethoxy)Anisole
CAS No.	1095544-42-5
Molecular Formula	C8H7BrF2O2
Molecular Weight	253.04 g/mol
Synonyms	1-Bromo-4-(difluoromethoxy)-2-methoxybenzene; 2-Methoxy-5-bromo-1-(difluoromethoxy)benzene; Benzene, 1-bromo-4-(difluoromethoxy)-2-methoxy-; 5-Bromo-2-(difluoromethoxy)anisole; 4-Bromo-1-(difluoromethoxy)-2-methoxybenzene
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Difluoromethoxy)Anisole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.