Description

1-Bromo-3,4-dimethoxy-2-fluorobenzene is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. Its unique halogenated and methoxylated structure makes it a valuable intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the reactive bromine substituent.
• Chemical Synthesis & Process Development: Employed in academic and industrial R&D for method development and scaling novel synthetic routes.
• Fluorine Chemistry Studies: Used as a model compound to study the effects of fluorine substitution on aromatic reactivity and physical properties.

Basic Information

Product Name	1-Bromo-3,4-dimethoxy-2-fluorobenzene
CAS No.	1095544-37-8
Molecular Formula	C8H8BrFO2
Molecular Weight	235.05 g/mol
Synonyms	2-Bromo-4,5-dimethoxy-1-fluorobenzene; 4,5-Dimethoxy-2-fluorobromobenzene; 3,4-Dimethoxy-2-fluorophenyl bromide; 2-Fluoro-4,5-dimethoxybromobenzene; Benzene, 1-bromo-3,4-dimethoxy-2-fluoro-; 1-Fluoro-2-bromo-4,5-dimethoxybenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3,4-dimethoxy-2-fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.