Description

2-[2-(2-{[(tert-Butoxy)Carbonyl]Amino}-6-Oxo-1,6-Dihydropyrimidin-5-Yl)-n-[2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Ethyl]Acetamido]Acetic Acid is a sophisticated, multi-functional building block designed for advanced organic synthesis and pharmaceutical research. This compound is critical for the development of novel peptide and heterocyclic-based therapeutics, offering precise control over molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, process development, and the synthesis of complex bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc/Boc-protected intermediate for the controlled assembly of complex peptide sequences.
• Pharmaceutical Intermediate: Used in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting enzyme inhibition or protein-protein interactions.
• Bioconjugation Chemistry: Acts as a linker or spacer molecule for attaching functional groups, labels, or other molecules to peptides or proteins.
• Combinatorial Chemistry Libraries: A valuable building block for creating diverse libraries of compounds for high-throughput screening in drug discovery.
• Proteomics Research: Employed in the synthesis of specialized probes and inhibitors used to study biological pathways and mechanisms.
• Chemical Biology Tool Development: Facilitates the creation of molecular tools for investigating cellular processes and target validation.

Basic Information

Product Name	2-[2-(2-{[(tert-Butoxy)Carbonyl]Amino}-6-Oxo-1,6-Dihydropyrimidin-5-Yl)-n-[2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Ethyl]Acetamido]Acetic Acid
CAS No.	1095275-70-9
Molecular Formula	C₃₃H₃₇N₅O₈
Molecular Weight	631.68 g/mol
Synonyms	Fmoc-Lys(Boc)-OH derivative; 5-{2-[2-(2-{[(tert-Butoxy)carbonyl]amino}acetamido)acetamido]ethyl}-6-oxo-1,6-dihydropyrimidin-2-yl]carbamic acid 9H-fluoren-9-ylmethyl ester; Nα-Fmoc-Nε-Boc-L-lysine-based heterocyclic building block; Fmoc-Asp(OBzl)-Lys(Boc)-OH analog; Peptide synthesis linker with Fmoc/Boc protection; Heterocyclic amino acid derivative; Protected dihydropyrimidine acetic acid
EINECS	Contact for details

Quality Control

Our production of this high-purity building block adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Quality assurance is guided by principles of Current Good Manufacturing Practice (cGMP) where applicable, and we can provide material suitable for use under quality systems like ISO 9001.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere to prevent degradation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Identification (IR)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.