Description

4-(2-Fluorophenyl)-2,3-Dihydro-1,3-Thiazol-2-One is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom and thiazolone core impart desirable biological and physicochemical properties. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Biology & Probe Development: Used in the design and synthesis of molecular probes and enzyme inhibitors for biochemical and pharmacological research.
• Material Science Precursor: Employed in the synthesis of specialized polymers, ligands for catalysis, and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	4-(2-Fluorophenyl)-2,3-Dihydro-1,3-Thiazol-2-One
CAS No.	1095051-79-8
Molecular Formula	C9H6FNO2S
Molecular Weight	211.21 g/mol
Synonyms	4-(2-Fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one; 2-Fluorophenylthiazolone; 2-(2-Fluorophenyl)-2,3-dihydrothiazol-5-one; 5-(2-Fluorophenyl)-2-thiazolidinone; 1095051-79-8; 4-(2-Fluorophenyl)-1,3-thiazol-2(3H)-one; 2-Fluoro-α-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)benzene
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorophenyl)-2,3-Dihydro-1,3-Thiazol-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.