Description

Cefoperazone Sodium is a semi-synthetic, broad-spectrum third-generation cephalosporin antibiotic. It is valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa. This API is essential for the formulation of injectable antibiotic preparations used in clinical settings to treat serious systemic infections. It serves the critical needs of pharmaceutical manufacturers and research institutions in the global healthcare sector.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the manufacture of sterile injectable antibiotic formulations.
• Hospital & Clinical Use: For the treatment of severe infections such as septicemia, peritonitis, and infections of the respiratory tract, biliary tract, and abdomen.
• Veterinary Medicine: Used in the development of antibiotic treatments for bacterial infections in animals.
• Research & Development: Serves as a reference standard and key intermediate in microbiological and pharmacological research.
• Combination Therapies: Often used in combination with β-lactamase inhibitors to enhance efficacy against resistant bacterial strains.

Basic Information

Product Name	Cefoperazone Sodium
CAS No.	1094606-34-4
Molecular Formula	C25H26N9NaO8S2
Molecular Weight	667.65 g/mol
Synonyms	Cefoperazone Sodium Salt; Cefobid; T-1551; Cefoperazonum Natricum; (6R,7R)-7-[[(2R)-2-[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium; Sodium (6R,7R)-7-[(R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido]-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Cefoperazone Sodium is manufactured under strict quality management systems. It is produced to meet high-purity standards suitable for pharmaceutical applications, with rigorous in-process and final release testing. Certificates of Analysis (COA) documenting identity, purity, and related substances are provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (10% solution)	4.5 - 6.5
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.