Description

3-(Trifluoromethyl)Cyclobutane-1-Carboxylic Acid is a high-value fluorinated cyclobutane derivative, a crucial building block in modern synthetic chemistry. Its unique structure, featuring a strained cyclobutane ring and a potent trifluoromethyl group, enables the precise modulation of molecular properties for advanced applications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors seeking to develop novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group improves efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalizing agent for specialty polymers, coatings, and liquid crystals with unique thermal and chemical resistance.
• Organic Synthesis Building Block: Employed in medicinal and process chemistry for constructing complex, fluorinated molecular architectures via ring-opening or further functionalization reactions.
• Ligand and Catalyst Development: Utilized in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	3-(Trifluoromethyl)Cyclobutane-1-Carboxylic Acid
CAS No.	1093750-93-6
Molecular Formula	C6H7F3O2
Molecular Weight	168.11 g/mol
Synonyms	3-(Trifluoromethyl)cyclobutane-1-carboxylic acid; 3-(Trifluoromethyl)cyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 3-(trifluoromethyl)-; 1-Carboxy-3-(trifluoromethyl)cyclobutane; 3-Trifluoromethylcyclobutane-1-carboxylic acid; 3-Trifluoromethylcyclobutanecarboxylic acid; 1093750-93-6
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Cyclobutane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.