Description

Caffeic Acid 4-β-D-Glucuronide is a specific glucuronide conjugate of the well-known phenolic acid, caffeic acid. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a major metabolite of caffeic acid, influencing bioavailability and biological activity. It is primarily utilized by researchers and manufacturers in the pharmaceutical, nutraceutical, and analytical reference standard sectors for metabolic studies, pharmacokinetic profiling, and as a high-purity standard for analytical methods.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active metabolite in studies investigating the pharmacokinetics, bioavailability, and metabolism of caffeic acid and related polyphenolic compounds.
• Analytical Chemistry: Serves as a high-purity certified reference material (CRM) for the quantification and identification of caffeic acid metabolites in biological samples (e.g., plasma, urine) using HPLC, LC-MS, or GC-MS.
• Nutraceutical & Functional Food Science: Employed in research to understand the bioactivity, stability, and health benefits of conjugated forms of dietary phenolics.
• Biochemical Pathway Studies: A key reagent for in vitro and in vivo studies on phase II metabolism, specifically glucuronidation pathways.
• Quality Control Laboratories: Used as an impurity standard or system suitability standard in the quality control of pharmaceutical products containing caffeic acid or its derivatives.

Basic Information

Product Name	Caffeic Acid 4-β-D-Glucuronide
CAS No.	1093679-71-0
Molecular Formula	C15H16O10
Molecular Weight	356.28 g/mol
Synonyms	Caffeic Acid 4-O-β-D-Glucuronide; (E)-3-(3,4-Dihydroxyphenyl)acrylic acid 4-O-β-D-glucopyranuronoside; Caffeic Acid 4-Glucuronide; 4-O-β-D-Glucuronosylcaffeic Acid; Caffeic Acid Glucuronide; CA4G; CAG
EINECS	Contact for details

Quality Control

Our Caffeic Acid 4-β-D-Glucuronide is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under desiccated conditions. Allow the product to equilibrate to room temperature in a dry environment before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.