Description

4-Hydroxy-2-Nitrobenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its bifunctional reactivity, offering both a phenolic hydroxyl group and a nitrile moiety adjacent to a nitro substituent, enabling precise molecular construction. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex intermediates, active ingredients, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with heterocyclic scaffolds or targeted biological activity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators, leveraging its reactive sites for structural diversification.
• Dye and Pigment Manufacturing: Serves as a starting material for the production of azo dyes and other complex colorants due to its nitro and hydroxyl functional groups.
• Ligand and Catalyst Development: Employed in the design of specialized chelating ligands for metal catalysis and coordination chemistry applications.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for engineering polymers with specific thermal or chemical resistance properties.
• Academic and Industrial R&D: A valuable reagent for methodological studies in nitration, cyanation, and nucleophilic aromatic substitution reactions.

Basic Information

Product Name	4-Hydroxy-2-Nitrobenzonitrile
CAS No.	1093203-96-3
Molecular Formula	C7H4N2O3
Molecular Weight	164.12 g/mol
Synonyms	2-Nitro-4-hydroxybenzonitrile; 4-Cyano-3-nitrophenol; 4-Hydroxy-2-nitrobenzenecarbonitrile; 2-Nitro-4-cyanophenol; Benzonitrile, 4-hydroxy-2-nitro-; Phenol, 4-cyano-3-nitro-; 4-Cyanoresorcinol 1-nitrate (obsolete); 4-Hydroxy-2-nitro-benzonitrile
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2-Nitrobenzonitrile is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support cGMP and ISO 9001 compliant production upon request for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.