Description

1-(2,5-Difluorophenyl)-2,2,2-Trifluoroethanone is a high-purity fluorinated aromatic ketone building block. This compound is valued for its unique trifluoroacetyl group and difluorophenyl ring, which are critical for modulating the electronic and steric properties of target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in the creation of fluorinated drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), especially in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorine substitution enhances bioactivity and environmental stability.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials requiring specific fluorinated aromatic units.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring novel organic reactions and synthesizing complex fluorinated molecules.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	1-(2,5-Difluorophenyl)-2,2,2-Trifluoroethanone
CAS No.	1092712-24-7
Molecular Formula	C8H3F5O
Molecular Weight	210.10 g/mol
Synonyms	2',5'-Difluoro-2,2,2-trifluoroacetophenone; 2,5-Difluorophenyl Trifluoromethyl Ketone; 1-(2,5-Difluorophenyl)-2,2,2-trifluoroethan-1-one; α,α,α-Trifluoro-2',5'-difluoroacetophenone; 2,5-Difluoro-α,α,α-trifluoroacetophenone; (2,5-Difluorophenyl)(trifluoromethyl)methanone; Trifluoro(2,5-difluorophenyl)methanone
EINECS	Contact for details

Quality Control

Our 1-(2,5-Difluorophenyl)-2,2,2-Trifluoroethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.