Description

3-Bromo-5-(Trifluoromethoxy)Phenylacetonitrile is a high-value, multi-functional chemical intermediate characterized by its bromine and trifluoromethoxy substituents. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the introduction of key functional groups into complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Fluorinated Compound Library: A critical starting material for generating diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated nitrile intermediates.

Basic Information

Product Name	3-Bromo-5-(Trifluoromethoxy)Phenylacetonitrile
CAS No.	1092461-34-1
Molecular Formula	C9H5BrF3NO
Molecular Weight	280.04 g/mol
Synonyms	2-(3-Bromo-5-(trifluoromethoxy)phenyl)acetonitrile; [3-Bromo-5-(trifluoromethoxy)phenyl]acetonitrile; 3-Bromo-5-(trifluoromethoxy)benzyl cyanide; α-(3-Bromo-5-(trifluoromethoxy)phenyl)acetonitrile; (3-Bromo-5-(trifluoromethoxy)phenyl)acetonitrile; 2-(3-Bromo-5-(trifluoromethoxyphenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Trifluoromethoxy)Phenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.