Description

Rage Antagonist Peptide CAS NO 1092460-91-7 is a synthetic peptide antagonist designed to specifically target and modulate the RAGE (Receptor for Advanced Glycation End-products) signaling pathway. This compound is of significant interest for research into inflammatory diseases, diabetes complications, and neurodegenerative disorders where RAGE plays a critical pathological role. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in preclinical drug discovery and mechanistic studies.

Application

• Biomedical Research: Used as a critical tool compound for investigating the role of the RAGE pathway in cellular models of inflammation, diabetes, and aging.
• Drug Discovery & Development: Serves as a reference standard and lead compound in screening assays for developing novel anti-inflammatory and neuroprotective therapeutics.
• Academic Studies: Employed in university and institutional labs to study signal transduction mechanisms related to chronic diseases and oxidative stress.
• In-vitro Diagnostics: May be used in the development of biochemical assays to measure RAGE activity or inhibition in biological samples.
• Preclinical Pharmacology: Applied in animal model studies to validate RAGE as a therapeutic target for conditions like atherosclerosis, Alzheimer's disease, and diabetic nephropathy.

Basic Information

Product Name	Rage Antagonist Peptide
CAS No.	1092460-91-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	RAGE Antagonist; RAGE Inhibitor Peptide; Advanced Glycation End-product Receptor Antagonist; sRAGE Antagonist Peptide; RAGE Signaling Blocker; 1092460-91-7; Receptor for Advanced Glycation End Products Antagonist
EINECS	Contact for details

Quality Control

Our Rage Antagonist Peptide is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including purity determination by HPLC and identity confirmation by mass spectrometry. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, controlled environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption. For long-term storage, keep under inert atmosphere or vacuum-sealed conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.