Description

n-(3-Chlorophenyl)-6-[[[(3-Chlorophenyl)Amino]Carbonyl]Amino]-9H-Purine-9-Carboxamide is a high-purity, synthetic purine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block or intermediate for creating novel therapeutic agents, particularly in oncology and targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel purine-based kinase inhibitors for cancer therapy.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and target validation studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex, high-value specialty chemicals.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology and drug discovery pathways.

Basic Information

Product Name	n-(3-Chlorophenyl)-6-[[[(3-Chlorophenyl)Amino]Carbonyl]Amino]-9H-Purine-9-Carboxamide
CAS No.	1092352-79-8
Molecular Formula	C19H13Cl2N7O2
Molecular Weight	442.26 g/mol
Synonyms	9H-Purine-9-carboxamide, N-(3-chlorophenyl)-6-[[[(3-chlorophenyl)amino]carbonyl]amino]-; 6-[(3-Chlorophenyl)ureido]-N-(3-chlorophenyl)-9H-purine-9-carboxamide; 1-(3-Chlorophenyl)-3-[(9-{[(3-chlorophenyl)amino]carbonyl}-9H-purin-6-yl)urea; Purine-9-carboxamide derivative (CAS 1092352-79-8); Bis(3-chlorophenyl) purine urea carboxamide
EINECS	Contact for details

Quality Control

Our n-(3-Chlorophenyl)-6-[[[(3-Chlorophenyl)Amino]Carbonyl]Amino]-9H-Purine-9-Carboxamide is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with complete chromatographic data are provided for every shipment. We can support development with research-grade to GMP-grade material as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.