Description

2-(4-(Bromomethyl)Phenoxy)Acetonitrile is a versatile brominated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and a nitrile functionality, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where its aromatic core provides structural diversity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce functional groups into polymer chains, enhancing material properties for specialty coatings and resins.
• Cross-coupling Reactions: The bromomethyl moiety acts as an excellent electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Ligand & Catalyst Development: Useful for constructing complex chelating ligands used in homogeneous catalysis and material science.

Basic Information

Item	Details
Product Name	2-(4-(Bromomethyl)Phenoxy)Acetonitrile
CAS No.	1092078-26-6
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	4-(Bromomethyl)phenoxyacetonitrile; (4-(Bromomethyl)phenoxy)acetonitrile; p-(Bromomethyl)phenoxyacetonitrile; 2-[4-(Bromomethyl)phenoxy]acetonitrile; Acetonitrile, 2-[4-(bromomethyl)phenoxy]-; 1092078-26-6; 4-Bromomethyl-phenoxy-acetonitrile
EINECS	Contact for details

Quality Control

Our 2-(4-(Bromomethyl)Phenoxy)Acetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.