Description

(1S,2S)-2-(Diphenylphosphino)-1,2-Diphenylethylamine is a high-purity chiral phosphine-amine ligand, essential for creating highly selective and efficient catalytic systems in asymmetric synthesis. Its value lies in enabling the production of enantiomerically pure intermediates for pharmaceuticals and fine chemicals, where stereochemical control is critical. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• As a key chiral ligand in asymmetric hydrogenation and other transition metal-catalyzed reactions.
• For the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and drug intermediates.
• In the development of novel catalysts for agrochemical and fragrance manufacturing.
• As a research tool in academic and industrial laboratories for studying stereoselective transformations.
• For the preparation of specialty polymers and advanced materials with controlled chirality.

Basic Information

Product Name	(1S,2S)-2-(Diphenylphosphino)-1,2-Diphenylethylamine
CAS No.	1091606-67-5
Molecular Formula	C26H24NP
Molecular Weight	381.45 g/mol
Synonyms	(1S,2S)-(-)-1,2-Diphenyl-2-((diphenylphosphino)amino)ethane; (S,S)-DIPAMP Analogue; (1S,2S)-DPEN-Phosphine; (S,S)-2-(Diphenylphosphino)-1,2-diphenylethylamine; (1S,2S)-N-[(Diphenylphosphino)]-1,2-diphenylethylamine; (S,S)-Chiraphos Derivative; (1S,2S)-Aminophosphine Ligand
EINECS	Contact for details

Quality Control

Our (1S,2S)-2-(Diphenylphosphino)-1,2-Diphenylethylamine is manufactured under strict quality control protocols to ensure a minimum purity of 97%. Each batch is characterized by NMR, HPLC, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) documenting all specifications are available upon request, supporting compliance with cGMP and internal quality standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Enantiomeric Excess (Chiral HPLC)	Min. 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.