Description

4-Amino-2-Bromo-5-Nitro-Benzonitrile is a high-purity, multi-functional aromatic nitrile building block of significant importance in advanced organic synthesis. Its unique structure, featuring amino, bromo, and nitro substituents, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its halogen and nitro groups for further functionalization.
• Material Science Research: Serves as a building block for organic electronic materials, such as non-linear optical (NLO) chromophores and conductive polymers.
• Dye and Pigment Chemistry: Acts as an intermediate in the synthesis of complex azo dyes and high-performance pigments due to its aromatic amine functionality.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create biaryl and other extended systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.

Basic Information

Product Name	4-Amino-2-Bromo-5-Nitro-Benzonitrile
CAS No.	1086965-24-3
Molecular Formula	C7H4BrN3O2
Molecular Weight	242.03 g/mol
Synonyms	2-Bromo-4-amino-5-nitrobenzonitrile; 5-Nitro-2-bromo-4-aminobenzonitrile; Benzonitrile, 4-amino-2-bromo-5-nitro-; 4-Amino-2-bromo-5-nitrobenzonitrile; 1086965-24-3; 2-Bromo-4-cyano-5-nitroaniline; 4-Cyano-2-bromo-5-nitroaniline
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Bromo-5-Nitro-Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.