Description

tert-Butyl n-(4-Bromo-2,5-Dimethylphenyl)Carbamate is a high-value, protected aniline derivative serving as a critical building block in advanced organic synthesis. Its primary commercial value lies in its role as a versatile synthetic intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-purity intermediates for API synthesis and lead optimization.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing substituted aniline moieties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the bromo and dimethyl substituents offer specific bioactivity.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reagent for protein labeling, bioconjugation, and the development of molecular probes due to its reactive bromine atom and protected amine.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed reactions such as Suzuki, Heck, and Buchwald-Hartwig amination, enabling complex carbon-carbon and carbon-nitrogen bond formation.
• Organic Synthesis Scaffold: The tert-butyloxycarbonyl (Boc) protecting group allows for selective deprotection, making it invaluable for multi-step synthetic routes in fine chemical production.

Basic Information

Item	Detail
Product Name	tert-Butyl n-(4-Bromo-2,5-Dimethylphenyl)Carbamate
CAS No.	1086392-05-3
Molecular Formula	C13H18BrNO2
Molecular Weight	300.19 g/mol
Synonyms	tert-Butyl (4-bromo-2,5-dimethylphenyl)carbamate; Carbamic acid, N-(4-bromo-2,5-dimethylphenyl)-, 1,1-dimethylethyl ester; BOC-4-Bromo-2,5-dimethylaniline; N-Boc-4-bromo-2,5-dimethylaniline; 1,1-Dimethylethyl N-(4-bromo-2,5-dimethylphenyl)carbamate; 4-Bromo-2,5-dimethylphenylcarbamic acid tert-butyl ester; tert-Butyl N-(4-bromo-2,5-dimethylphenyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(4-Bromo-2,5-Dimethylphenyl)Carbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.