Description

Bis[2-(Di-1-Adamantylphosphino)Ethyl]Amine, Min. 97% is a sophisticated, high-purity organophosphorus ligand featuring a unique diadamantyl-substituted structure. This compound matters as a critical catalyst component in advanced cross-coupling reactions, enabling the synthesis of complex pharmaceutical intermediates and fine chemicals with high selectivity and yield. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new catalytic processes.

Application

• Catalyst Ligand for Cross-Coupling Reactions: Serves as a highly effective ligand in palladium- or nickel-catalyzed Suzuki-Miyaura, Heck, and Buchwald-Hartwig amination reactions.
• Pharmaceutical Intermediate Synthesis: Enables the construction of complex carbon-carbon and carbon-heteroatom bonds in the synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Research & Development: Used in the catalytic synthesis of novel herbicides, fungicides, and insecticides requiring specific stereochemistry.
• Material Science Catalysis: Applied in the development of novel polymers and advanced organic electronic materials via catalytic polymerization or functionalization.
• Asymmetric Catalysis Development: Its bulky, chiral-like adamantyl groups make it a candidate for research into new asymmetric hydrogenation and C-H activation catalysts.
• Academic & Industrial R&D: A valuable tool for exploring new reaction methodologies and mechanistic studies in homogeneous catalysis.

Basic Information

Item	Detail
Product Name	Bis[2-(Di-1-Adamantylphosphino)Ethyl]Amine, Min. 97%
CAS No.	1086138-36-4
Molecular Formula	C44H68NP2
Molecular Weight	664.96 g/mol
Synonyms	Bis[2-(Diadamantylphosphino)ethyl]amine; N,N-Bis[2-(di-1-adamantylphosphino)ethyl]amine; 1,1'-(Phosphinidynedi-2,1-ethanediyl)bis[1-adamantane]amine derivative; Di-1-Adamantylphosphinoethylamine dimer; PNAdP ligand (Adamantyl variant); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of Bis[2-(Di-1-Adamantylphosphino)Ethyl]Amine adheres to stringent internal quality standards to ensure batch-to-batch consistency and a minimum purity of 97%. Identity and purity are confirmed via advanced analytical techniques including NMR (1H, 13C, 31P) and HPLC. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should only be opened in an inert environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.