Description

Biotin-Peg6-Azide is a high-purity, heterobifunctional crosslinking reagent designed for advanced bioconjugation and click chemistry applications. This compound is essential for researchers and developers requiring precise, site-specific labeling of biomolecules, such as proteins and antibodies, for diagnostic and therapeutic purposes. It is a critical tool for professionals in pharmaceutical R&D, proteomics, and the development of targeted drug delivery systems and diagnostic assays.

Application

• Site-specific biotinylation of proteins, antibodies, and peptides for assay development.
• Construction of Antibody-Drug Conjugates (ADCs) via copper-free click chemistry with DBCO or cyclooctyne-functionalized payloads.
• Preparation of functionalized surfaces and nanoparticles for biosensor and diagnostic device fabrication.
• Labeling of oligonucleotides and other biomolecules for pull-down assays and affinity purification.
• Proteomics research, including the enrichment and isolation of protein complexes.
• Development of targeted therapeutic agents and imaging probes in preclinical research.
• Functionalization of hydrogels and biomaterials for controlled release and cell culture applications.

Basic Information

Product Name	Biotin-Peg6-Azide
CAS No.	1085938-09-5
Molecular Formula	C31H56N8O10S
Molecular Weight	732.9 g/mol
Synonyms	Biotin-PEG6-N3; Biotin-PEG6-Azide; 5-((6-Azido-3,6,9,12,15,18-hexaoxahenicos-1-yl)oxy)-5-oxopentyl)biotinamide; Biotinamidohexanoic acid-PEG6-azide; Biotinamidocaproyl-PEG6-azide; Biotin-(PEG)6-N3; N-(6-(Biotinamido)hexanoyl)-1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-azide
EINECS	Contact for details

Quality Control

Our Biotin-Peg6-Azide is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.