Description

3-Fluoro-4-(Hydroxymethyl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a boronic acid group and a hydroxymethyl substituent on a fluorinated aromatic ring, makes it an exceptionally versatile reagent for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, as well as by manufacturers of advanced materials and liquid crystal displays.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require fluorinated aromatic components.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and organic electronic materials.
• Liquid Crystal Manufacturing: Employed in the synthesis of fluorinated liquid crystal compounds for high-performance displays.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of boronic acid-based sensors and affinity ligands.
• Organic Synthesis Research: A valuable reagent for academic and industrial R&D exploring new C-C bond formation methodologies and complex molecule construction.

Basic Information

Product Name	3-Fluoro-4-(Hydroxymethyl)Phenylboronic Acid
CAS No.	1082066-52-1
Molecular Formula	C7H8BFO3
Molecular Weight	169.95 g/mol
Synonyms	(3-Fluoro-4-(hydroxymethyl)phenyl)boronic acid; 4-Borono-2-fluorobenzyl alcohol; 2-Fluoro-4-(hydroxymethyl)benzeneboronic acid; 3-Fluoro-4-(hydroxymethyl)benzeneboronic acid; B-(3-Fluoro-4-(hydroxymethyl)phenyl)boronic acid; 1082066-52-1; 3-Fluoro-4-hydroxymethylphenylboronic Acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Hydroxymethyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports applications requiring GMP-grade starting materials and ensures compliance with global regulatory standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.