Description

(2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is a high-value boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific fluorinated aromatic structures for enhanced activity and stability.
• Material Science: Precursor for creating organic electronic materials, such as ligands for OLEDs (Organic Light-Emitting Diodes) and components for organic photovoltaics.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new carbon-carbon bond formation strategies and creating compound libraries.
• Ligand Synthesis: Serves as a starting material for the preparation of sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	(2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol
CAS No.	1082066-29-2
Molecular Formula	C13H18BFO3
Molecular Weight	252.09 g/mol
Synonyms	2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanol; (2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol; 4-(Benzyloxy)-2-fluorophenylboronic acid pinacol ester; 2-Fluoro-4-(hydroxymethyl)phenylboronic acid pinacol ester; (4-(Hydroxymethyl)-3-fluorophenyl)boronic acid pinacol ester; Pinacol (2-fluoro-4-(hydroxymethyl)phenyl)boronate
EINECS	Contact for details

Quality Control

Our (2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.