Description

3-Bromo-4-Methyl-5-Nitrobenzonitrile is a high-purity, multi-functional aromatic nitrile building block used in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research, where its unique substitution pattern enables precise structural modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing nitrile and nitro functional groups.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogen and nitro substituents for bioactivity.
• Material Science Research: Acts as a building block for creating specialized polymers, liquid crystals, and organic electronic materials due to its rigid, substituted benzene core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create more complex biaryl structures.
• Dye and Pigment Intermediate: Utilized in the synthesis of advanced dyes and organic pigments where the nitro and cyano groups influence color and stability.

Basic Information

Product Name	3-Bromo-4-Methyl-5-Nitrobenzonitrile
CAS No.	1082041-95-9
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	5-Nitro-3-bromo-4-methylbenzonitrile; Benzonitrile, 3-bromo-4-methyl-5-nitro-; 3-Bromo-4-methyl-5-nitrobenzenecarbonitrile; 4-Methyl-3-bromo-5-nitrobenzonitrile; 1082041-95-9; 3-Br-4-Me-5-NO2-BnCN
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Methyl-5-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and should be stored away from light. Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.