Description

4-Methoxy-Piperidine-4-Carbonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined stereochemical center. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily sought by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical producers engaged in innovative drug development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents.
• CNS Drug Research: Used in the development of ligands and modulators for neurological targets.
• Antiviral Compound Synthesis: Serves as a structural component in the creation of potential antiviral candidates.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Utilized for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Custom Synthesis: A starting material for the preparation of more complex, proprietary piperidine derivatives.

Basic Information

Product Name	4-Methoxy-Piperidine-4-Carbonitrile Hydrochloride
CAS No.	1082040-34-3
Molecular Formula	C8H15ClN2O
Molecular Weight	190.67 g/mol
Synonyms	4-Methoxypiperidine-4-carbonitrile hydrochloride; 4-Cyano-4-methoxypiperidine hydrochloride; 4-Methoxy-4-piperidinecarbonitrile hydrochloride; 4-Piperidinecarbonitrile, 4-methoxy-, hydrochloride; 4-Methoxy-4-cyanopiperidine HCl
EINECS	Contact for details

Quality Control

Our 4-Methoxy-Piperidine-4-Carbonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.