Description

Propanoic Acid, 3,3,3-Trifluoro-2-Oxo-, Hydrate (1:1) is a specialized fluorinated organic compound that serves as a key building block in advanced chemical synthesis. This high-purity intermediate is valued for its ability to introduce the trifluoromethyl ketone moiety, a functional group of significant interest in modern material and pharmaceutical science. It is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for creating novel molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), particularly those targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms can improve biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials to modify solubility and electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and inhibitors for studying enzyme function.

Basic Information

Product Name	Propanoic Acid, 3,3,3-Trifluoro-2-Oxo-, Hydrate (1:1)
CAS No.	1081801-99-1
Molecular Formula	C3H3F3O3 • H2O
Molecular Weight	156.06 g/mol (anhydrous basis)
Synonyms	3,3,3-Trifluoro-2-oxopropanoic acid hydrate; Trifluoropyruvic acid monohydrate; 2-Oxo-3,3,3-trifluoropropanoic acid hydrate; 3,3,3-Trifluoropyruvic acid hydrate; TFPA hydrate; α-Keto-β,β,β-trifluoropropionic acid hydrate
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 3,3,3-Trifluoro-2-Oxo-, Hydrate (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	10.0% - 13.0% (Theoretical for monohydrate: ~11.5%)
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.