Description

4-[(1Z)-2-(2-Fluorophenyl)-n-Hydroxyethanimidoyl]-3-Hydroxyphenoxy}Acetonitrile is a sophisticated, high-purity chemical intermediate designed for advanced synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a unique structural motif for targeted molecular construction. It is primarily needed by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate and scale complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor-binding profiles.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or plant growth regulators that require a fluorinated phenolic backbone.
• Ligand Synthesis: Serves as a starting material for creating complex chelating agents or catalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Material Science: Potential monomer or additive for advanced polymers and functional materials where the hydroxyphenoxy and nitrile groups impart specific properties.
• Chemical Biology Probes: Utilized in the design of fluorescent tags, enzyme inhibitors, or other molecular probes for diagnostic and research applications.

Basic Information

Product Name	4-[(1Z)-2-(2-Fluorophenyl)-n-Hydroxyethanimidoyl]-3-Hydroxyphenoxy}Acetonitrile
CAS No.	1081139-68-5
Molecular Formula	C₁₇H₁₃FN₂O₃
Molecular Weight	312.30 g/mol
Synonyms	2-[4-[(1Z)-N-Hydroxy-2-(2-fluorophenyl)ethanimidoyl]-3-hydroxyphenoxy]acetonitrile; 4-[(1Z)-2-(2-Fluorophenyl)-N-hydroxyethanimidoyl]-3-hydroxyphenoxyacetonitrile; (Z)-2-(4-((2-(2-Fluorophenyl)-N-hydroxyacetimidoyl)-3-hydroxyphenoxy)acetonitrile; 1081139-68-5; Acetonitrile, 2-[4-[(1Z)-N-hydroxy-2-(2-fluorophenyl)ethanimidoyl]-3-hydroxyphenoxy]-; Fluorinated hydroxyphenoxy acetonitrile derivative; N-Hydroxy intermediate CAS 1081139-68-5
EINECS	Contact for details

Quality Control

Our 4-[(1Z)-2-(2-Fluorophenyl)-n-Hydroxyethanimidoyl]-3-Hydroxyphenoxy}Acetonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.