Description

3-(2,6-Difluorophenyl)Cyclobutan-1-One is a high-purity, synthetically valuable organic building block featuring a cyclobutanone core flanked by a difluorinated aromatic ring. This compound is a critical intermediate in modern pharmaceutical and agrochemical research, enabling the construction of complex molecules with enhanced metabolic stability and bioavailability. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the difluorophenyl group can improve lipophilicity and target binding.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials that require rigid, fluorinated aromatic components.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3-(2,6-Difluorophenyl)Cyclobutan-1-One
CAS No.	1080636-34-5
Molecular Formula	C10H8F2O
Molecular Weight	182.17 g/mol
Synonyms	3-(2,6-Difluorophenyl)cyclobutanone; 2,6-Difluorophenyl cyclobutanone; Cyclobutanone, 3-(2,6-difluorophenyl)-; 1080636-34-5; 3-(2,6-Difluorophenyl)cyclobutan-1-one; 3-(2,6-Difluorophenyl)-1-cyclobutanone
EINECS	Contact for details

Quality Control

Our 3-(2,6-Difluorophenyl)Cyclobutan-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with client specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.