Description

n-Acetyl-S-[2-Amino-1-(Hydroxymethyl)-2-Oxoethyl]-L-Cysteine-1,1-Dimethylethyl Ester is a sophisticated, high-purity protected cysteine derivative designed for advanced pharmaceutical synthesis and biochemical research. This compound serves as a critical building block for the controlled introduction of cysteine residues in complex peptide and protein engineering projects, where precise molecular architecture is paramount. It is essential for researchers and manufacturers in the fields of peptide drug development, proteomics, and the synthesis of novel therapeutic agents requiring specific thiol functionality.

Application

• Peptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Bioconjugation Chemistry: Facilitates site-specific labeling and modification of proteins and antibodies for diagnostic and therapeutic applications.
• Proteomics Research: Employed in the study of protein structure, function, and interactions, particularly involving cysteine residues.
• Chemical Biology Tool Development: Serves as a precursor for synthesizing probes and inhibitors that target thiol-dependent enzymes and pathways.

Basic Information

Product Name	n-Acetyl-S-[2-Amino-1-(Hydroxymethyl)-2-Oxoethyl]-L-Cysteine-1,1-Dimethylethyl Ester
CAS No.	1079950-10-9
Molecular Formula	C12H22N2O6S
Molecular Weight	322.38 g/mol
Synonyms	N-Acetyl-S-(2-amino-1-(hydroxymethyl)-2-oxoethyl)-L-cysteine tert-butyl ester; Fmoc-Cys(Acm)-OH tert-butyl ester derivative; S-(2-Acetamido-2-carboxyethyl)-L-cysteine tert-butyl ester (protected form); Ac-Cys(Acm)-OtBu; tert-Butyl N-acetyl-S-(2-amino-1-(hydroxymethyl)-2-oxoethyl)-L-cysteinate; Protected L-Cysteine derivative; Acetamidomethyl (Acm) protected cysteine tert-butyl ester
EINECS	Contact for details

Quality Control

Our n-Acetyl-S-[2-Amino-1-(Hydroxymethyl)-2-Oxoethyl]-L-Cysteine-1,1-Dimethylethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and GMP-grade applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent in-house specifications that align with the demands of pharmaceutical intermediate and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.