Description

Valdoxan-D4 is a deuterated isotopologue of the active pharmaceutical ingredient agomelatine, specifically designed for use as an internal standard in analytical chemistry. This high-purity compound is essential for ensuring the accuracy and reliability of quantitative analyses, particularly in pharmacokinetic and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers who require precise and traceable reference materials for method development and validation using techniques like LC-MS/MS.

Application

• Internal Standard for LC-MS/MS analysis in bioanalytical studies.
• Quantitative reference material for pharmacokinetic (PK) and bioavailability research.
• Method development and validation in pharmaceutical quality control laboratories.
• Metabolite identification and profiling studies in drug discovery.
• Calibration standard for ensuring accuracy in clinical trial sample analysis.
• Use in forensic and anti-doping analysis for precise quantification.

Basic Information

Item	Detail
Product Name	Valdoxan-D4
CAS No.	1079389-44-8
Molecular Formula	C15H17D4NO2
Molecular Weight	247.35 g/mol (approx.)
Synonyms	Agomelatine-d4; N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide-d4; S 20098-d4; S20098-d4; Valdoxan deuterated; Deuterated Agomelatine
EINECS	Contact for details

Quality Control

Our Valdoxan-D4 is manufactured under strict quality control protocols to ensure the highest isotopic purity and chemical integrity required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from advanced spectroscopic and chromatographic tests, including NMR and HPLC-MS. We adhere to relevant industry standards for reference materials to guarantee reliable and consistent performance in your critical assays.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.