Description

4-Desmethoxy-4-Nitro Omeprazole Sulfone is a key advanced pharmaceutical intermediate, specifically a derivative of the proton pump inhibitor omeprazole. This compound is of significant value in the research and development of novel active pharmaceutical ingredients (APIs) and in the synthesis of related therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel proton pump inhibitors and related drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic compounds targeting acid-related disorders.
• Process Development & Scale-up: Serves as a reference standard and starting material for optimizing synthetic routes in pilot and commercial-scale API manufacturing.
• Analytical Reference Standard: Employed in quality control laboratories for method development, validation, and impurity profiling of omeprazole-based pharmaceuticals.
• Academic & Institutional Research: Utilized in universities and research institutes for pharmacological studies and advanced organic synthesis projects.

Basic Information

Item	Detail
Product Name	4-Desmethoxy-4-Nitro Omeprazole Sulfone
CAS No.	1076199-93-3
Molecular Formula	C16H14N4O5S
Molecular Weight	374.37 g/mol
Synonyms	4-Desmethoxy-4-nitroomeprazole sulfone; 5-Methoxy-2-[[(4-nitro-3-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sulfone derivative; Omeprazole sulfone nitro derivative; 4-Nitro omeprazole sulfone analog; 4-Desmethoxy omeprazole sulfone nitro compound; 1H-Benzimidazole, 5-methoxy-2-[[(4-nitro-3-pyridinyl)methyl]sulfinyl]-, 1-oxide
EINECS	Contact for details

Quality Control

Our 4-Desmethoxy-4-Nitro Omeprazole Sulfone is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.