Description

n-(4-Chloro-2-Trifluoroacetyl-6-Methoxyphenyl)-2,2-Dimethylpropanamide is a high-purity, specialized organic intermediate featuring a unique trifluoroacetyl group and a pivalamide moiety. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical compounds and agrochemicals, where its specific halogenated and fluorinated structure imparts desirable biological activity and metabolic stability. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and process chemistry, enabling the exploration of new chemical entities and optimization of synthetic routes.
• Material Science Precursor: Potential use in the development of advanced organic materials, such as liquid crystals or polymers with specific fluorinated properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	n-(4-Chloro-2-Trifluoroacetyl-6-Methoxyphenyl)-2,2-Dimethylpropanamide
CAS No.	1076199-86-4
Molecular Formula	C14H15ClF3NO3
Molecular Weight	337.72 g/mol
Synonyms	2,2-Dimethyl-N-[4-chloro-2-(trifluoroacetyl)-6-methoxyphenyl]propanamide; 4-Chloro-2-(trifluoroacetyl)-6-methoxy-2,2-dimethylpropananilide; Propanamide, N-[4-chloro-2-(trifluoroacetyl)-6-methoxyphenyl]-2,2-dimethyl-; Pivalamide Derivative CAS 1076199-86-4; Trifluoroacetyl Chloromethoxyphenyl Pivalamide
EINECS	Contact for details

Quality Control

Our n-(4-Chloro-2-Trifluoroacetyl-6-Methoxyphenyl)-2,2-Dimethylpropanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your most critical synthesis stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.