Description

Ropinirole n-Oxide is a key pharmaceutical intermediate and metabolite of the active drug substance Ropinirole. This compound is of significant importance for research and development in the pharmaceutical industry, particularly in the study of drug metabolism, pharmacokinetics, and the synthesis of related compounds. It is primarily utilized by pharmaceutical R&D laboratories, analytical service providers, and manufacturers engaged in the development of advanced neurological and dopaminergic therapies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis and research of Ropinirole and its analogs.
• Metabolite Reference Standard: Used as an analytical standard in bioanalytical studies for the identification and quantification of Ropinirole metabolites in biological matrices.
• Drug Metabolism and Pharmacokinetics (DMPK) Research: Essential for studying the metabolic pathways, stability, and clearance of Ropinirole.
• Impurity Profiling: Employed as a known impurity or degradation product standard to ensure the purity and quality of Ropinirole Active Pharmaceutical Ingredient (API).
• Preclinical and Clinical Research: Supports investigative studies in neurological disorders, including Parkinson's disease and Restless Legs Syndrome (RLS).
• Chemical Research: Serves as a substrate for further chemical modification and exploration of novel chemical entities within its class.

Basic Information

Product Name	Ropinirole n-Oxide
CAS No.	1076199-41-1
Molecular Formula	C16H24N2O2
Molecular Weight	276.38 g/mol
Synonyms	4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one N-Oxide; Ropinirole N-Oxide; Ropinirole Metabolite; SKF-101468 N-Oxide; 2H-Indol-2-one, 4-[2-(dipropylamino)ethyl]-1,3-dihydro-, 1-oxide
EINECS	Contact for details

Quality Control

Our Ropinirole n-Oxide is manufactured under strict quality control protocols to ensure high purity and consistency, suitable for research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.