Description

4-Boc-1-(1,4-Benzodioxan-2-Ylcarbonyl)Piperazine CAS NO 1076199-22-8 is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core protected by a tert-butoxycarbonyl (Boc) group and functionalized with a 1,4-benzodioxane moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing central nervous system (CNS) and cardiovascular therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• API Development: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the design and creation of molecular probes for studying biological processes and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) offering bespoke chemical synthesis services.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and pharmacological studies.

Basic Information

Product Name	4-Boc-1-(1,4-Benzodioxan-2-Ylcarbonyl)Piperazine
CAS No.	1076199-22-8
Molecular Formula	C19H26N2O5
Molecular Weight	362.42 g/mol
Synonyms	1,4-Benzodioxan-2-carboxylic acid, 1-(1,1-dimethylethoxy)carbonyl-4-piperazinyl ester; tert-Butyl 4-[(1,4-benzodioxan-2-yl)carbonyl]piperazine-1-carboxylate; 1-Boc-4-(1,4-benzodioxane-2-carbonyl)piperazine; 4-(1,4-Benzodioxane-2-carbonyl)-N-Boc-piperazine; Piperazine, 4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our 4-Boc-1-(1,4-Benzodioxan-2-Ylcarbonyl)Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.